Digitizing mass spectrometry data to explore the chemical diversity and distribution of marine cyanobacteria and algae

Natural product screening programs have uncovered molecules from diverse natural sources with various biological activities and unique structures.However, much is yet underexplored and additional information is hidden in these exceptional collections.We applied untargeted mass spectrometry approaches to capture the chemical space and dispersal patt

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Linear interaction between replication and transcription shapes DNA break dynamics at recurrent DNA break Clusters

Abstract Recurrent DNA break clusters (RDCs) are replication-transcription collision hotspots; many are unique to neural progenitor cells.Through high-resolution replication sequencing and a capture-ligation assay in mouse neural ENDURA STRESS PET progenitor cells experiencing replication stress, we unravel the replication features dictating RDC lo

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Treatment of avian malaria in captive African penguins (Spheniscus demersus) by the combination of atovaquone and proguanil hydrochloride

Avian malaria, a vector-borne disease caused by Plasmodium spp., poses significant threats to various bird populations, particularly captive penguins like the endangered African penguin (Spheniscus demersus).Penguins, originating from regions with low malaria prevalence, are highly susceptible when housed in malaria-permissive areas.This study eval

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Evaluating the removal efficiency of emerging contaminants in a gravity-driven membrane bioreactors GD-MBR under various aeration conditions for primary wastewater treatment

Conventional wastewater treatment processes have shown limited efficiency in removing emerging contaminants (EC), including organic micropollutants (OMPs) thus posing risks due to the safe discharge and reuse of wastewater effluent due to the presence of antibiotic-resistant bacteria and antibiotic resistance genes (ARG).Membrane technologies are b

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